KMID : 0351619670080020322
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Kyungpook Medical Journal 1967 Volume.8 No. 2 p.322 ~ p.329
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Studies on Serum Protein and Lippprotein in the Field of Pediatrics
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Abstract
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For the determinations of serum protein and lipoprotein partitions in age differences and under different feeding conditions including those of maternal and cord blood(newborn infant) sera, a total of 146 subjects in 8 different groups were studied by means of Spinco Model R Paper Electrophoresis System. The following results were thus obtained.
1. Slightly decreasing tendency of the total protein tivas observed in the under 6 months old breast-fed group than that of the cord blood group but without any significant difference, hower-er it was significantly increased in the 6-24 months old breast-fed group than in the under 6 months old breast-fed group. Inspite of sho~virag slightly decreased value of the total protein in the early childhood group and slightly increa~ed value of it in the later childhood group, there were nor observed any significant differences between age groups o~-er the age of 24 m~~nths. It was lower in the cow¢¥s milk-fed orphan in rant group than in the same age breast-fed group with the significant difference being shown especially in the group of 6-24 months old.
2. The albumin value vas slightly increased in the breast-fed infant group than in the cordblood grouf+ without any significant difference and thereafter it was remarkably decreased in the groups of age over 2 year old than in the breast-fed infant group. It was remarkably decreased in the cow¢¥s milk-fed orphan infant group than in the breast-fed infant group.
3. There were observed no differences of ai globulin values between groups of each ages and the breast-f~~d infant and the cow¢¥s milk-fed orphan infant groups. The cr.,- and ~3-globulin values were significantly increased in the under 6 months old group than in the cord blood group, but thereafter there were observed no differences between each. age group including groups of the breast-fed and the cow¢¥s milk-fed orphan infants. The r-globulin value was remarkably decreased in the group of under 6 months old breast-fed infant than in the cord blood group and then a gradually incr~:asing tendency was observed by the advancement of age. It was significantly increased in the cow¢¥s milk-fed orphan infant group than in the breast-fed infant group.
4. The lipoprotein ratio was remarkably decreased in t;1e cord blood group. And then a gradually increasing tendency was seen by the advancement t+f age with the exception of its decreasing tendency in the later childhood group. Even though a somewhat decreasing tendency was revealed in the group of the under 2 year old orphan than in the breast-fed of the same age, there were no significant differences between them.
5. The albumin value was markedly decreased in th~~ maternal group as compared with the cord blood group; A/G ratio was below 1.0 in the maternal group. However ~7/a lipoprotein ratio was remarkably increased in the maternal group..
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